Myanmar : Big Issues With HIV & TB Médecins Sans Frontières (MSF), the largest provider of HIV treatment in Myanmar, released a report today highlighting the urgency of treating HIV and multi-drug resistant Tuberculosis (MDR-TB) in their country - Myanmar used to be called Burma. As many as 85,000 people are going without retroviral treatments and another 9,300 are infected with MDR-TB each year, while as few as 300 get any treatment... Wed, 22 Feb 2012 14:00:00 PST Back to Top How To Become A Family Nurse Practitioner Online If you are a licensed registered nurse you may well be able to enroll in a new online Master of Science in Nursing degree program with a strong focus in Family Nurse Practitioner. This program, offered by Herzing University Online, is available in 27 states in the USA. The University says it is an opportunity for a licensed registered nurse to become a family nurse practitioner. Dr... Wed, 22 Feb 2012 11:00:00 PST Back to Top Endogenous Cushing's Syndrome - FDA Approves Korlym (Mifepristone) The U.S. Food and Drug Administration has approved Korlym (mifepristone) to control hyperglycemia (high blood sugar levels) in adults with endogenous Cushing's syndrome, who have type 2 diabetes or glucose intolerance, who remained unresponsive to previous surgery or are not eligible candidates for surgery. Pregnant women should never take Korlym (contraindicated). Until the FDA approved Korlym for the treatment of endogenous Cushing's syndrome, there were no approved medications to treat the disorder... Wed, 22 Feb 2012 10:00:00 PST Back to Top Obesity - New Clues By Age And Stage, Australia Researchers have found that one fourth of students in Australian secondary schools are either overweight or obese, affecting lifestyle and socioeconomic status. The study, published in the February 20 issue of the Medical Journal of Australia - a publication of the Australian Medical Association, was funded by Cancer Councils around Australia and the National Heart Foundation. The study examined 12,188 students and found that just under one quarter were either obese (5%) or overweight (18%)... Wed, 22 Feb 2012 10:00:00 PST Back to Top The Deadly Impact Of Atherothrombosis A report published in the February 20 issue of the Medical Journal of Australia, a publication of the Australian Medical Association, reveals that nearly 40% of individuals with extensive atherothrombotic disease will experience a cardiovascular event within one year. The team, led by professor Christopher Reid from Monash University, set out to determine the most deadliest forms of atherothrombosis - a combination of blood clots and plaque on artery walls that causes blockage of blood flow... Wed, 22 Feb 2012 10:00:00 PST Back to Top Close Contact With Rodents Is A Health Hazard A case report published in the February 20 issue of the Medical Journal of Australia, reveals that a 26-year-old woman from Adelaide who enjoyed cuddling and kissing her pet rats contracted Streptobacillus moniliformis infection (rat bite fever). The disease is potentially fatal and could become more prevalent as rodent ownership increases. The Medical Journal of Australia is a publication of the Australian Medical Association. According to the report by Dr Lito Papanicolas, a registrar at SA Pathology, and coauthors, although S... Wed, 22 Feb 2012 10:00:00 PST Back to Top Adult Pneumococcal Vaccines - How Cost Effective Are They? According to a computer-based cost-effectiveness analysis in the February issue of JAMA, recommending the use of the 13-valent pneumococcal conjugate vaccine (PCV13) could possibly prevent more pneumococcal disease than the current 23-valent pneumococcal polysaccharide vaccine (PPSV23) recommendations. The costs would remain reasonably economic, however the researchers point out that their findings are sensitive to several assumptions... Wed, 22 Feb 2012 09:00:00 PST Back to Top Fake Drugs Increasing On The Net And Finding Their Way Into Legitimate Supplies Fake drugs are increasingly being sold on the Internet in a global counterfeit medicines market that has doubled in the last five years to more than $75 million. The medicines, many of which are life-threatening, have even turned up in the legitimate supply chain and found their way into pharmacies, according a review by Dr Graham Jackson and colleagues published in the March issue of the IJCP, the International Journal of Clinical Practice... Wed, 22 Feb 2012 09:00:00 PST Back to Top Homocysteine Levels Not Linked To Coronary Artery Disease Risk This week's PLoS Medicine reports on a comprehensive study that reveals that levels of the amino acid, homocysteine, have no significant effect on the risk of developing coronary heart disease. This concludes the ongoing argument of the previously suggested benefits of lowering homocysteine with folate acid. According to earlier studies, high blood levels of homocysteine might be a modifiable risk factor for coronary heart disease... Wed, 22 Feb 2012 09:00:00 PST Back to Top Raw Milk Causes Most Dairy-related Outbreaks Of Diseases Unpasteurized milk, also known as raw milk, is proportionally responsible for 150 times more disease outbreaks than pasteurized milk, a new report issued by the CDC's (Center for Disease Control and Prevention) Emerging Infectious Diseases has revealed. The authors also explained that dairy-related disease outbreaks in US states where raw milk is legal occur at twice the rate compared to other states. In this study, researchers gathered data on dairy-related outbreaks from 1993 through 2006 throughout the United States. During the study period, the USA produced approximately 2... Wed, 22 Feb 2012 09:00:00 PST Back to Top Huntington's Disease - Blocking HDACs May Be The Way The February 21 issue of the open access journal PLoS Biology reveals that researchers from the National University of Ireland Galway have made an important scientific discovery in the battle against Huntington's disease. Worldwide, more than 100,000 people are affected by Huntington's disease, an incurable, inherited, neurodegenerative disorder which causes uncontrolled movements, emotional disturbances, and severe mental deterioration. Estimates show that another 300,000 are likely to develop symptoms in their lifetime... Wed, 22 Feb 2012 09:00:00 PST Back to Top Peptide Helps Improve Learning And Memory Although there are several drugs and experimental conditions that can block cognitive function and impair learning and memory, researchers have recently shown that some drugs can actually improve cognitive function. The new multi-national study, published in the 21 February issue of the open-access journal PLoS Biology, reveals that these findings may implicate scientists' understanding of cognitive disorders like Alzheimer's disease. There are trillions of neuronal connections, called synapses in the human brain that are dynamic and constantly change in strength and property... Wed, 22 Feb 2012 09:00:00 PST Back to Top Female Heart Attack Patients Have A Higher In-Hospital Mortality Rate Than Men A study in the February issue of JAMA, reports that female heart attack patients are more likely to go to hospital without chest pain and have a much higher rate of in-hospital death following a heart attack, compared to men of the same age group. The study, by John G. Canto, M.D., M.S.P.H., of the Watson Clinic and Lakeland Regional Medical Center, Lakeland, Fla., and colleagues, analyzed the links between; the gender of the patient, the symptoms of myocardial infarction (heart attack) they develop, and risk of death in hospital... Wed, 22 Feb 2012 08:00:00 PST Back to Top Traumatic Brain Injury - Clazosentan May Block Harmful Effects A study in rats has found that a new medication called clazosentan, may be effective in blocking the harmful effects of traumatic brain injury (TBI). The study will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. Michael Kaufman, study author, a second year medical student at Wayne State University School of Medicine in Detroit, and member of the American Academy of Neurology, explained: "There are currently no primary treatments for TBI, so this research provides hope that effective treatments can be developed... Wed, 22 Feb 2012 05:00:00 PST Back to Top Large Waists Linked To Memory Difficulties In HIV Patients A study published in the print issue of Neurology®, the medical journal of the American Academy of Neurology, suggests that a larger waistline may be associated with a greater risk of decreased mental functioning in HIV-positive individuals. J. Allen McCutchan, M.D., MSc, of the University of California, San Diego, and lead researcher of the study, explained: "Interestingly, bigger waistlines were linked to decreased mental functioning more than was general obesity... Wed, 22 Feb 2012 05:00:00 PST Back to Top Apps On "Prescription" From Your GP General practitioners in the UK could soon be "prescribing" cheap or free smartphone apps to help their patients manage their health and medical conditions, according to news released on Wednesday by the Department of Health. Health Secretary Andrew Lansley said: "So many people use apps every day to keep up with their friends, with the news, find out when the next bus will turn up or which train to catch. I want to make using apps to track blood pressure, to find the nearest source of support when you need it and to get practical help in staying healthy the norm... Wed, 22 Feb 2012 03:00:00 PST Back to Top Some Insulin Production Found In Long-Term Type 1 Diabetes Massachusetts General Hospital (MGH) research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent loss of pancreatic function. The study results appear in the March issue of Diabetes Care. "Traditionally, it was thought that beta cell function completely ceased in patients with advanced type 1 diabetes... Wed, 22 Feb 2012 02:00:00 PST Back to Top Research Offers Insights Into Addiction - Cocaine And The Teen Brain When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, Yale and other scientists have found. Now two new studies by a Yale team identify key genes that regulate this response and show that interfering with this reaction dramatically increases a mouse's sensitivity to cocaine. The findings may help explain why risk of drug abuse and addiction increase so dramatically when cocaine use begins during teenage years. The results were published in the Feb. 14 and Feb. 21 issues of the Journal of Neuroscience... Wed, 22 Feb 2012 02:00:00 PST Back to Top Strengthening The Intestinal Barrier May Prevent Cancer In The Rest Of The Body A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests. It appears that the hormone receptor guanylyl cyclase C (GC-C) - a previously identified tumor suppressor that exists in the intestinal tract - plays a key role in strengthening the body's intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens. A team led by Scott Waldman, M.D., Ph.D... Wed, 22 Feb 2012 02:00:00 PST Back to Top Oral Bacterium Newly Identified Linked To Heart Disease And Meningitis A novel bacterium, thought to be a common inhabitant of the oral cavity, has the potential to cause serious disease if it enters the bloodstream, according to a study in the International Journal of Systematic and Evolutionary Microbiology. Its identification will allow scientists to work out how it causes disease and evaluate the risk that it poses. The bacterium was identified by researchers at the Institute of Medical Microbiology of the University of Zurich and has been named Streptococcus tigurinus after the region of Zurich where it was first recognised. S... Wed, 22 Feb 2012 02:00:00 PST Back to Top Electronic Health Records Alert Pediatricians To Obese Patients Electronic health records and embedded tools can alert and direct pediatricians so they can better manage the weight of children and teenagers, according to a new Kaiser Permanente study published online in The Journal of Pediatrics... Wed, 22 Feb 2012 02:00:00 PST Back to Top Better Understanding Of Cancer Drugs Following Discovery Of Cell Energy Sensor Mechanism Johns Hopkins and National Taiwan University researchers have discovered more details about how an energy sensing "thermostat" protein determines whether cells will store or use their energy reserves. In a report in Nature, the researchers showed that a chemical modification on the thermostat protein changes how it's controlled. Without the modification, cells use stored energy, and with it, they default to stockpiling resources. When cells don't properly allocate their energy supply, they can die off or become cancerous... Wed, 22 Feb 2012 02:00:00 PST Back to Top College Students Comfortable With Biobanks, Willing To Donate Genetic Material For Research A majority of college students is receptive to donating blood or other genetic material for scientific research, according to a new study from Southern Methodist University, Dallas. In what appears to be the first study to gauge college students' willingness to donate to a genetic biobank, the study surveyed 250 male and female undergraduate and graduate students. Among those surveyed, 64 percent said they were willing to donate to a biobank, said study author Olivia Adolphson... Wed, 22 Feb 2012 02:00:00 PST Back to Top Overweight Americans May Risk Kidney Damage When Attempting Weight Loss With 1 in 5 overweight Americans suffering from chronic kidney disease, Cleveland Clinic researchers analyzed the nutritional and lifestyle habits of overweight adults, finding that their methods included diets and diet pills that may cause further kidney damage... Wed, 22 Feb 2012 02:00:00 PST Back to Top Faith-Based Advocacy And Childhood Obesity Faith-based advocacy has been cited as a valuable tool in combating childhood obesity, but evidence is needed to support this assertion and to define how the link between advocacy and policy can contribute to promoting permanent lifestyle changes. This article is part of a special issue of the journal Childhood Obesity celebrating the second anniversary of First Lady Michelle Obama's Let's Move! initiative. The issue includes a special Foreword by Mrs. Obama and is available free on the Childhood Obesity website... Wed, 22 Feb 2012 02:00:00 PST Back to Top Nerve Regeneration For The Future The carnage evident in disasters like car wrecks or wartime battles is oftentimes mirrored within the bodies of the people involved. A severe wound can leave blood vessels and nerves severed, bones broken, and cellular wreckage strewn throughout the body - a debris field within the body itself. It's scenes like this that neurosurgeon Jason Huang, M.D., confronts every day. Severe damage to nerves is one of the most challenging wounds to treat for Huang and colleagues... Wed, 22 Feb 2012 01:00:00 PST Back to Top Researchers Reveal Role Of Protein Mutation In Parkinson's Disease Purdue University researchers revealed how a mutation in a protein shuts down a protective function needed to prevent the death of neurons in Parkinson's disease, possibly opening the door to new drug strategies to treat the disorder. Fred Regnier, the J.H. Law Distinguished Professor of Chemistry, and Jean-Christophe Rochet, an associate professor of medicinal chemistry and molecular pharmacology, led the team that discovered how the protein DJ-1, which plays a significant role in protecting neurons from damage, is shut down by a subtle mutation... Wed, 22 Feb 2012 01:00:00 PST Back to Top Weaning From Gluten May Be Pointless For Many People who do not have celiac disease and believe they have "non-celiac gluten sensitivity" may be weaning themselves off gluten unnecessarily, researchers from the University of Pavia, Pavia, Italy, reported in Annals of Internal Medicine. The authors added that the majority of people who avoid gluten have "nonceliac gluten sensitivity" - those with celiac disease are a minority among gluten avoiders. Individuals with celiac disease have a condition in which the lining of the small intestine becomes damaged; undermining their ability to absorb nutrients from food properly... Wed, 22 Feb 2012 01:00:00 PST Back to Top Free-Access Online Journal Launched By American Heart Association The American Heart Association has launched the online-only open-access Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (JAHA) - packed with free peer-reviewed research on heart disease and stroke. "We envision JAHA as a forum for high quality original articles that cover the full range of cardiovascular science, including basic science, translational science, clinical trials and epidemiological and outcomes research," said Joseph A. Vita, M.D., JAHA editor in chief... Wed, 22 Feb 2012 01:00:00 PST Back to Top Drugs That Affect Serotonin Signaling May Combat Bone Loss Scientists have long known that calcium leaches from the bones both during lactation and in certain types of cancer. The driver behind these phenomena is a molecule called parathyroid hormone related protein (PTHrP), which is secreted by the mammary glands. The signal that regulates the secretion of PTHrP, and where this other unknown molecule exerts its influence, has remained a mystery... Wed, 22 Feb 2012 01:00:00 PST Back to Top A Mechanism To Improve Learning And Memory There are a number of drugs and experimental conditions that can block cognitive function and impair learning and memory. However, scientists have recently shown that some drugs can actually improve cognitive function, which may have implications for our understanding of cognitive disorders such as Alzheimer's disease. The new research is reported 21 February in the open-access journal PLoS Biology. The study, led by Drs. Jose A... Wed, 22 Feb 2012 01:00:00 PST Back to Top New Discovery In Fight Against Huntington's Disease Researchers at National University of Ireland Galway have made a significant scientific discovery in the fight against Huntington's disease. The novel findings are published 21 February in the online, open access journal PLoS Biology. Huntington's disease is an incurable, inherited, neurodegenerative disorder that causes uncontrolled movements, emotional disturbances, and severe mental deterioration. It affects over 100,000 people worldwide, with another 300,000 likely to develop symptoms in their lifetime... Wed, 22 Feb 2012 01:00:00 PST Back to Top Helping To Control Malaria Via Text Messaging In this week's PLoS Medicine, Dejan Zurovac and colleagues from the Kenya Medical Research Institute/Wellcome Trust Research Program, Nairobi, Kenya discuss six areas where text messaging could improve the delivery of health services and health outcomes in malaria in Africa, including three areas transmitting information from the periphery of the health system to malaria control managers and three areas transmitting information to support management of malaria patients... Wed, 22 Feb 2012 01:00:00 PST Back to Top Researchers Compare Antimalarial Drugs And Their Effects Over The Plasmodium Lifecycle In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei, and Plasmodium yoelii. These results provide a valuable guide to help researchers decide which drugs and compounds show most promise as potential future antimalarial drugs for blocking the transmission of malaria... Wed, 22 Feb 2012 01:00:00 PST Back to Top No Link Found Between High Blood Homocysteine Levels And Coronary Heart Disease A comprehensive study in this week's PLoS Medicine shows levels of the amino acid, homocysteine, have no meaningful effect on the risk of developing coronary heart disease, closing the door on the previously suggested benefits of lowering homocysteine with folate acid once and for all... Wed, 22 Feb 2012 01:00:00 PST Back to Top First Model Of Aggressive Ovarian Cancer Demonstrates Immune System's Active Role In Tumor Progression Aggressive ovarian tumors begin as malignant cells kept in check by the immune system until, suddenly and unpredictably, they explode into metastatic cancer. New findings from scientists at The Wistar Institute demonstrate that ovarian tumors don't necessarily break "free" of the immune system, rather dendritic cells of the immune system seem to actively support the tumor's escape. The researchers show that it might be possible to restore the immune system by targeting a patient's own dendritic cells... Wed, 22 Feb 2012 00:00:00 PST Back to Top Link Between Size Of Brain Region And Conformity Identified By Scientists Every generation has its James Dean: the rebel who refuses to follow the path beaten by their peers. Now, a new study in Current Biology has found a link between the amount of grey matter in one specific brain region and an individual's likelihood of conforming to social pressures. Individuals are presented with many choices in life, from political alignments through to choosing which sandwich to eat for lunch. Their eventual decisions can be influenced by the options chosen by those around them... Wed, 22 Feb 2012 00:00:00 PST Back to Top For Patients With Advanced Hepatitis C, The Benefits Of Treatment Outweigh The Costs A towering $60,000 bill, a year of fierce, flu-like symptoms and a running risk of depression are among the possible costs of two new hepatitis C treatments. But according to Stanford University health policy researchers, they might be worth it. Using a computer model of hepatitis C disease - which accounts for different treatments, outcomes, disease stages and genetics - a research team led by Jeremy Goldhaber-Fiebert, PhD, found that new triple-therapies for genotype-1 hepatitis C are cost-effective for patients with advanced disease. Their results were published Feb... Wed, 22 Feb 2012 00:00:00 PST Back to Top News From The Annals Of Internal Medicine: Feb. 21 2012 1. Death Rates from Viral Hepatitis Infections Steadily Increase From 1999 - 2007, Now Surpass HIV-related Deaths in U.S. Middle-aged Americans Disproportionately Affected by "Silent Epidemic" Approximately 3.2 million people in the United States are infected with chronic hepatitis C virus (HCV), a leading cause of liver disease, cirrhosis, and death. Chronic hepatitis infection is most prevalent among people born from 1945 through 1965, and most of them do not know they are infected... Wed, 22 Feb 2012 00:00:00 PST Back to Top Reformulated Imatinib Eliminates Morphine Tolerance In Lab Studies By reformulating the common cancer drug imatinib (Gleevec®), researchers have eliminated morphine tolerance in rats - an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center. Narcotics such as morphine are a mainstay of chronic pain treatment. Over time, tolerance to the pain-relieving effects of these drugs can develop, requiring increasing doses to control pain. In some cases, narcotics become ineffective... Wed, 22 Feb 2012 00:00:00 PST Back to Top Ring-Like Protein Complex Helps Ensure Accurate Protein Production In fairy tales, magic rings endow their owners with special abilities: the ring makes the wearer invisible, fulfils his wishes, or otherwise helps the hero on the path to his destiny. Similarly, a ring-like structure found in a protein complex called 'Elongator' has led researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Institut de Genetique et Biologie Moleculaire et Cellulaire (IGBMC) in Strasbourg, France, in exciting new directions... Wed, 22 Feb 2012 00:00:00 PST Back to Top Potential For Development Of Tailor-Made Anticancer Agents Following Mapping Of Protein Inhibitors A team of researchers at Karolinska Institutet has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs. The study is presented in the journal Nature Biotechnology, and will hopefully contribute to new cancer therapies with fewer detrimental side effects. PARP1 is a protein with enzymatic activity that governs repair of DNA damage in our cells... Wed, 22 Feb 2012 00:00:00 PST Back to Top Problem Behavior In Toddlers May Be Due To Over-Reactive Parenting Researchers have found that parents who anger easily and over-react are more likely to have toddlers who act out and become upset easily. The research is an important step in understanding the complex link between genetics and home environment. In the study, researchers from Oregon State University, Oregon Social Learning Center, and other institutions collected data in 10 states from 361 families linked through adoption - and obtained genetic data from birth parents as well as the children... Wed, 22 Feb 2012 00:00:00 PST Back to Top New Compound To Fight Strep Throat Infection Researchers have discovered a promising alternative to common antibiotics used to fight the bacteria that causes strep throat. In an article published in the Proceedings of the National Academy of Sciences, the scientists discussed how their discovery could fight the infection with a reduced risk of antibiotic resistance. By screening tens of thousands of small molecules, the team from the University of Missouri and University of Michigan identified a class of chemical compounds that significantly reduced the severity of group A Streptococcus (GAS) bacteria infection in mice... Wed, 22 Feb 2012 00:00:00 PST Back to Top Cancer Cells Destroyed By Blocking Telomerase But Resistance, Progression Provoked Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in Cell. "Telomerase is overexpressed in many advanced cancers, but assessing its potential as a therapeutic target requires us to understand what it does and how it does it," said senior author Ronald DePinho, M.D., president of The University of Texas MD Anderson Cancer Center... Wed, 22 Feb 2012 00:00:00 PST Back to Top Prostate Cancer Progression Driven By Telomere Failure, Telomerase Activation Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell. In a strain of mice engineered to develop prostate cancer, all mice that went through this two-step process developed lethal cancer and 25 percent had the disease spread to the spine. Two groups of mice that avoided this cycle developed only precancerous lesions or localized prostate cancer... Wed, 22 Feb 2012 00:00:00 PST Back to Top Early Cancer Detection Via New Blood Test: Research In The Early Stages Of Clinical Trials A simple blood test is being developed by researchers at Ben-Gurion University of the Negev (BGU) and Soroka University Medical Center in Beer-Sheva, Israel that may provide early detection of many types of cancer. Prof. Kapelushnik of BGU's Faculty of Health Sciences and his team developed a device that illuminates cancer cells with less than a teaspoon of blood. The test uses infrared light to detect miniscule changes in the blood of a person who has a cancerous growth somewhere, even before the disease has spread... Wed, 22 Feb 2012 00:00:00 PST Back to Top Evolution Of Staph 'Superbug' Traced Between Humans And Food Animals A strain of the potentially deadly antibiotic-resistant bacterium known as MRSA has jumped from food animals to humans, according to a new study involving two Northern Arizona University researchers. Paul Keim, Regents' professor and director of NAU's Center for Microbial Genetics and Genomics, and Lance Price, NAU faculty member and director of the Center for Food Microbiology and Environmental Health at the Translational Genomics Research Institute, collaborated with scientists at 20 institutions around the world on the study published in the online journal mBio... Wed, 22 Feb 2012 00:00:00 PST Back to Top Evolutionary Secret Of Blood Vessels Unlocked By Research Scientists The ability to form closed systems of blood vessels is one of the hallmarks of vertebrate development. Without it, humans would be closer to invertebrates (think mollusks) in design, where blood simply washes through an open system to nourish internal organs. But vertebrates evolved closed circulation systems designed to more effectively carry blood to organs and tissues. Precisely how that happened has remained a clouded issue... Wed, 22 Feb 2012 00:00:00 PST Back to Top Promising New Compound For Treating Stroke Researchers at the University of Copenhagen have designed, produced and patented a new chemical compound for the possible treatment of brain damage caused by stroke. The compound binds 1,000 times more effectively to the target protein in the brain than the potential drug currently being tested on stroke victims. The results of biological tests have just been published in the renowned journal PNAS - Proceedings of the National Academy of Sciences of the United States of America.. More than 140,000 people die each year from stroke in the United States... Wed, 22 Feb 2012 00:00:00 PST Back to Top Possible New Target For Cancer Therapy - Energy Network Within Cells Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB. Within each cell, mitochondria are constantly splitting in two, a process called fission, and merging back into one, called fusion... Wed, 22 Feb 2012 00:00:00 PST Back to Top Identification Of 'Stealth' Properties Of Cancer-Causing Genetic Mutations Scientists have discovered that cancer-causing genetic mutations have better-disguised electronic signatures than other mutations - a trait which could help them fly under the radar of the body's defence mechanisms. Results of a new study by physicists at the University of Warwick and in Taiwan hint at the possibility that one day the electronic properties of DNA could play a role in early diagnosis and detection of mutation hotspots. Researchers drew on the power of supercomputers to model every possible mutation for 162 disease-related genes, a total of 5 billion calculations... Wed, 22 Feb 2012 00:00:00 PST Back to Top The Molecular Basis Of Touch Sensation A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered. They found that in mice in which they had removed the c-Maf gene in the nerve cells, touch sensation is impaired. This similarly applies to human carriers of a mutant c-Maf gene. People with such a mutation suffer at a young age from cataracts, a clouding of the lens which typically affects the elderly... Wed, 22 Feb 2012 00:00:00 PST Back to Top Depression And The Aging Process Stress has numerous detrimental effects on the human body. Many of these effects are acutely felt by the sufferer, but many more go 'unseen', one of which is shortening of telomere length. Telomeres are protective caps on the ends of chromosomes and are indicators of aging, as they naturally shorten over time. However, telomeres are also highly susceptible to stress and depression, both of which have repeatedly been linked with premature telomere shortening. The human stress response is regulated by the hypothalamic-pituitary-adrenal axis, or HPA axis... Wed, 22 Feb 2012 00:00:00 PST Back to Top Babies Benefit When Their Mothers Are Vaccinated For Influenza During Pregnancy Vaccinating pregnant women against the influenza virus appears to have a significant positive effect on birth weight in babies, according to a study published in CMAJ (Canadian Medical Association Journal). The study, a randomized controlled trial involving 340 healthy pregnant women in Bangladesh in the third trimester, looked at the effect of immunization with the influenza vaccine on babies born to vaccinated mothers. It was part of the Mother'sGift project looking at the safety and efficacy of pneumococcal and influenza vaccines in pregnant women in Bangladesh... Wed, 22 Feb 2012 00:00:00 PST Back to Top Plastic Surgery Really Does Make People Look Younger Plastic surgery seems to make people look about 8.9 years younger than their actual age, researchers from the University of Toronto and NorthShore University Health System reported in Archives of Facial Plastic Surgery. Jeremy P. Warner, M.D., and team set out to determine how much younger esthetic facial surgical procedures made people look, in order to measure surgical success. They gathered data on 60 patients who had all undergone facial plastic surgeries. They were aged between 45 and 72 years... Wed, 22 Feb 2012 00:00:00 PST Back to Top MRSA CC398 Linked With Tetracycline And Methicillin Drug Resistance A recent study by the Translational Genomic Research Institute (TGen), published in the online journal mBio, reveals that a strain of MRSA, a bacterium which is untreatable by the use of antibiotics, is now not only found in livestock, but also in humans. The strain MRSA CC398, which is a strain of methicillin-resistant Staphylococcus aureus, also known as a Staph infection, is believed to have probably started in humans, spread to livestock, and is back infecting humans. It is believed to have become antibiotic resistant while in the animals... Tue, 21 Feb 2012 14:00:00 PST Back to Top Heart Attack With No Chest Pain In Women More Common Than In Men A study in the February issue of JAMA , shows that women are more likely than men to be admitted to a hospital without chest pain, and also have a higher rate of in-hospital death after a heart attack, compared with men of the same age group, even though these differences decrease, as people get older. The article's background information states: "Optimal recognition and timely management of myocardial infarction [MI; heart attack], especially for reducing patient delay in seeking acute medical care, is critical. The presence of chest pain/discomfort is the hallmark symptom of MI... Tue, 21 Feb 2012 13:00:00 PST Back to Top Pediatric Combo Vaccine Linked To Slight Risk Of Febrile Seizure A study, published in JAMA of almost 400,000 children, showed that children had an increased risk of febrile seizures, a convulsion that occurs secondary to a rapid increase in body temperature on the day of the first and second vaccination, with the combined diphtheria-tetanus toxoids-acellular pertussis-inactivated poliovirus - Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine. However, the overall risk was low, with researchers observing no higher risk of epilepsy in those who were vaccinated, compared with those who were not... Tue, 21 Feb 2012 13:00:00 PST Back to Top What Causes Leg Pain? Leg pain refers to any kind of pain that occurs between the heels and the pelvis. There are many reasons for leg pain, and not all of them are caused by a problem that originates in the leg; some injuries or spinal problems can cause aches and pains in the leg(s). Leg pain can be long-term, transitory, intermittent, acute, or slowly progressive. Pain may affect just part of the leg, such as the knee, or the whole limb. Leg pain may be felt as tingling, sharp, dull, an ache, or a stabbing sensation... Tue, 21 Feb 2012 13:00:00 PST Back to Top
Bone Health Update
Osteoporosis is no longer considered an old person’s disease. At age 4o bone
mass begins to dramatically decrease. The good news? Simple lifestyle changes
you make now can keep your skeleton strong.
1. THE DYNAMIC DUO calcium and vitamin D are the dream team
that helps prevent osteoporosis and debilitating fractures. Found in dairy
products, the mineral calcium increases bone density, while vitamin D, which the
body produces in response to sunlight, helps with calcium absorption.
Unfortunately, most women don’t get enough of either nutrient, so ask your
doctor about supplements. Experts recommend a daily dose of 1,000 to 1,400
mg of calcium and 800 to 1,000 IU of vitamin D.
2. THE PERFECT PAIRING by forcing your skeleton to work
harder, weight-bearing exercises help strengthen your bones, says Deena Goodman,
a physical therapist in Los Angeles. So in addition to trying to squeeze in 30
minutes of walking on most days, do these easy exercises three times a week:
Sit-to-stand
- Sit upright in a chair, keeping your feet shoulder-width apart.
- Push your heels into the ground and stand up slowly, back straight,
without using your arms.
- Stand for one second, then gradually lower your body back to the sitting
position (again, no hands).
- Repeat this simple up-and-down motion 10 times.
Step up
- Standing, place your right foot on a curb, the bottom step of a staircase
or a sturdy footstool.
- Then, lift your left foot onto the step too.
- Step back down, leading with your left foot.
- Repeat 10 times, and then do reps starting with your left foot.
3. A COUPLE OF SNACKS lean proteins and whole grains are key
to a healthy diet, but they’re usually highly Acidic – and excess acid breaks
down bone. To maintain a balance, bulk up on fruits and veggies, which contain
alkaline compounds (the opposite of acids).
Source: Jane Bianchi, Family Circle May 2009
PS: There are two delicious fruit and veggie recipes that can be used as 2 of
the 5 daily servings. If interested, send us an e-mail to receive the recipes.
Back to Top
Unique Conference Inspires Nurses
Source: INOVA Inside Edition July 2007
Earlier this year, a special
gathering of nurses took place locally that brought Iranian nurses from several
countries and many states together to celebrate their unique bond and shared
commitment to nursing. Organized by Inova's own Simin Hayati, RN, MSN, and a
fellow graduate of National Iranian Oil Company School of Nursing (NIOC-SON),
Nooshin Javan, RN, MSN, the conference goals included reuniting graduates from
the school to renew the spirit for the nursing profession and its service to
humanity, while also remembering the school where the received degrees, which
was destroyed during wartime.
This spring's gathering was the second time Iranian nurses gathered together,
following the inaugural reunion event in April 2005 involving the school's
alumni. This year's event did not restrict attendance to school ties, but was
open to any Iranian nurse. The conference captured the attention of Nursing
Spectrum magazine and parts of the speaker's remarks were even broadcast by
Voice of America and heard around the world!
You may recognize Simin as the author of the poem "Nurses are Beautiful,"
which has been shared with many audiences, including the attendees of the annual
Edelman conference for Inova nurses held during Nurses Week. Simin has been a
nurse for 43 years and has spent 18 with Inova - most recently in case
management. Her words are inspiring and the poem is excerpted below:
Nurses are Beautiful
Nurses are beautiful, their souls, and their bodies are beautiful. Their
minds are radiating positive energy toward their patient's healing. Their
minds are beautiful. Yes they are beautiful.
Their mouths bring hope and
caring words. Their smiles help their patients overcome their sadness and
their voices erase their patient's anger and hate. Their smiles are
beautiful. Yes, they are beautiful.
They are beautiful in both appearance and souls. Yes, nurses are
beautiful.
Poem by: Simin Hayati
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A Trip to Abadan Above The Clouds
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The History of Nursing in Iran
This book is not available at the moment but it is ready for publication.
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Inova Nurses Organizes Unusual Reunion
Source: INOVA Inside Edition, July 2005
When Inova VNA Home Health nurse Simin Hayati set out to organize a reunion
of her fellow nursing school graduates, she faced a daunting task. For this was
no ordinary reunion.
Hayati is a graduate of the National Iranian Oil Company School if Nurses
(NOIC), an Iranian nursing school that was destroyed during the Iran-Iraq war.
She and her schoolmate Nooshin Java, a nurse-mentor who runs the nurse retention
program for Dimensions Healthcare System in Maryland, spent six months tracking
down NOIC graduates around the world. In April, more than 85 nurses from 10
countries, ranging in age from 30 to 80, gathered in Las Vegas to share
memories, honor colleagues and celeberate the joy of finding one another
again.
"This was an amazing thing," says Hayati, who is grateful for Inova's support
as she worked with javan to organize the reunion. "Locating these nurses took
many months of hard work, We were thrilled so many could attend."
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